Drug industry treading water on R&D productivity












LONDON (Reuters) – Drug companies are becoming more efficient in hunting for new treatments, though this has yet to be reflected in improved investment returns, according to a report on Tuesday.


Low productivity in research labs is the biggest single challenge facing the global pharmaceutical industry, which is struggling to replenish its medicine chest after a wave of patient expiries that peaked this year.












While companies are getting more compounds into late-stage development – reflecting a smarter and more targeted approach to research and development (R&D) – turning those new products into big commercial winners is an uphill struggle.


That reflects growing caution among governments about buying costly new drugs, as well as the arrival of more specialist products that address relatively small patient populations.


The latest annual study of R&D productivity by Deloitte and Thomson Reuters found that the number of new drug approvals increased by around 30 percent, yet the expected revenue from these medicines actually fell by a similar amount.


In total, the world’s 12 top pharmaceutical companies had 41 new drugs approved, with combined forecast revenues of $ 211 billion, while the year-earlier tally was 32 products with expected revenues of $ 309 billion.


In effect, the industry is treading water in the fight to deliver better returns on the billions of dollars ploughed into the hunt for new drugs each year.


With an average internal rate of return (IRR) from R&D in 2012 of 7.2 percent – against 7.7 percent and 10.5 percent in the two preceding years – Big Pharma is barely covering its average cost of capital, estimated at around 7 percent.


Nonetheless, there are some encouraging signs. In particular, 10 of the 12 companies tracked in the report showed an improvement in replenishing their stock of late-stage experimental drugs.


“We’ve seen returns stabilizing and there are signs on the horizon that the situation might turn around, depending on how successful the industry is at commercializing new assets as they come through,” said Julian Remnant, head of Deloitte’s European R&D advisory practice.


At $ 1.1 billion, the average cost of developing a new medicine has remained fairly constant, although it varies hugely between companies, since this figure includes money spent on drugs that ultimately fail.


For the most successful company in the group, the average cost of developing a drug was just $ 315 million, while at the other extreme one firm spent $ 2.8 billion.


The companies analyzed in the study were Pfizer, Roche, Novartis, Sanofi, GlaxoSmithKline, Johnson & Johnson, AstraZeneca, Merck & Co, Eli Lilly, Bristol-Myers Squibb, Takeda and Amgen.


The study calculated IRRs for these companies by estimating the future value of sales from products in final-stage Phase III clinical trials, or those submitted for regulatory approval, using standard industry benchmarks for success rates.


(Editing by Louise Heavens)


Medications/Drugs News Headlines – Yahoo! News


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UK economy ‘not as bad in 2012′













The British Chambers of Commerce (BCC) has increased its forecast for UK growth for 2012, but still expects the economy to shrink.












The UK will shrink by 0.1% this year, less than the 0.4% contraction it had predicted previously, the BCC said.


That is “entirely due to the stronger-than-expected” growth in the last quarter, helped by the Olympic Games.


But it now sees growth of 1% for the whole of 2013, down from the 1.2% it had forecast in September.


“As we wait in anticipation for the chancellor to deliver his Autumn Statement tomorrow, our new forecast highlights the challenges still facing the UK economy over the months and years ahead,” said John Longworth, director-general of the BCC.


“The fact remains that growth is still too weak. Thankfully, we have businesses here in the UK that are ambitious, determined and resilient.”


Chancellor George Osborne gives the Autumn Statement on Wednesday. Over the weekend, he admitted that curbing the UK’s financial deficit was “taking longer” than planned.


The BCC said that public sector borrowing would be £104.1bn for 2012/13 – more than £12bn higher that it had predicted in March.


“Many firms are expanding exports, investing, and creating jobs, but more must be done to support the aspirations of growing companies that will be the wealth creators of tomorrow,” Mr Longworth said.


Last month, it emerged that the UK economy had bounced back from recession in the three months to September.


The economy grew by 1.0%, after contracting for the previous nine months. The UK has still not recovered the levels of output seen before the financial crisis in 2008.


For 2014, the BCC cut the forecast to 1.8%, from 2.2%.


The BCC said that the lower GDP growth forecasts for 2013 and 2014 were due to the fact that the “international environment has worsened, as growth forecasts for world trade, for the eurozone, and for other major economies have been revised down in recent months” and that more spending cuts were likely in the UK.


BBC News – Business


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Official: Syria moving chemical weapons components












WASHINGTON (AP) — U.S. and allied intelligence have detected Syrian movement of chemical weapons components in recent days, a senior U.S. defense official said Monday, as the Obama administration strongly warned the Assad regime against using them.


A senior defense official said intelligence officials have detected activity around more than one of Syria‘s chemical weapons sites in the last week. The defense official spoke on condition of anonymity because he was not authorized to speak publicly about intelligence matters.












Secretary of State Hillary Rodham Clinton, in Prague for meetings with Czech officials, reiterated President Barack Obama‘s declaration that Syrian action on chemical weapons was a “red line” for the United States that would prompt action.


“We have made our views very clear: This is a red line for the United States,” Clinton told reporters. “I’m not going to telegraph in any specifics what we would do in the event of credible evidence that the Assad regime has resorted to using chemical weapons against their own people. But suffice it to say, we are certainly planning to take action if that eventuality were to occur.”


Syria said Monday it would not use chemical weapons against its own people. The Ministry of Foreign Affairs said Syria “would not use chemical weapons — if there are any — against its own people under any circumstances.”


Syria has been careful never to confirm that it has any chemical weapons.


The use of chemical weapons would be a major escalation in Assad’s crackdown on his foes and would draw international condemnation. In addition to causing mass deaths and horrific injuries to survivors, the regime’s willingness to use them would alarm much of the region, particularly neighboring states, including Israel.


At the White House, press secretary Jay Carney said, “We are concerned that in an increasingly beleaguered regime, having found its escalation of violence through conventional means inadequate, might be considering the use of chemical weapons against the Syrian people. And as the president has said, any use or proliferation of chemical weapons by the Syrian regime would cross a red line for the United States. “


Administration officials would not detail what that response might be.


Although Syria is one of only seven nations that have not signed the Chemical Weapons Treaty, it is a party to the 1925 Geneva Protocol that bans the use of chemical weapons in war. That treaty was signed in the aftermath of World War I, when the effects of the use of mustard gas and other chemical agents outraged much of the world.


Clinton didn’t address the issue of the fresh activity at Syrian chemical weapons depots, but insisted that Washington would address any threat that arises.


An administration official said the trigger for U.S. action of some kind is the use of chemical weapons or movement with the intent to use or provide them to a terrorist group like Hezbollah. The U.S. is trying to determine whether the recent movement detected in Syria falls into any of those categories, the official said. The administration official was speaking on condition of anonymity this person was not authorized to speak publicly about the issue.


The senior defense official said the U.S. does not believe that any Syrian action beyond the movement of components is imminent.


An Israeli official said if there is real movement on chemical weapons, it would require a response. He didn’t say what that might be and spoke on condition of anonymity pending a formal government response to the reports of the latest activities.


Israeli officials have repeatedly expressed concerns that Syrian chemical weapons could slip into the hands of Hezbollah or other anti-Israel groups, or even be fired toward Israel in an act of desperation by Syria.


Syria is believed to have several hundred ballistic surface-to-surface missiles capable of carrying chemical warheads.


Its arsenal is a particular threat to the American allies, Turkey and Israel, and Obama singled out the threat posed by the unconventional weapons earlier this year as a potential cause for deeper U.S. involvement in Syria’s civil war. Up to now, the United States has opposed military intervention or providing arms support to Syria’s rebels for fear of further militarizing a conflict that activists say has killed more than 40,000 people since March 2011.


Clinton said that while the actions of President Bashar Assad‘s government have been deplorable, chemical weapons would bring them to a new level.


“We once again issue a very strong warning to the Assad regime that their behavior is reprehensible, their actions against their own people have been tragic,” she said. “But there is no doubt that there’s a line between even the horrors that they’ve already inflicted on the Syrian people and moving to what would be an internationally condemned step of utilizing their chemical weapons.”


Activity has been detected before at Syrian weapons sites, believed to number several dozen.


Defense Secretary Leon Panetta said in late September the intelligence suggested the Syrian government had moved some of its chemical weapons in order to protect them. He said the U.S. believed that the main sites remained secure.


Asked Monday if they were still considered secure, Pentagon press secretary George Little declined to comment about any intelligence related to the weapons.


Senior lawmakers were notified last week that U.S. intelligence agencies had detected activity related to Syria’s chemical and biological weapons, said a U.S. intelligence official, speaking on condition of anonymity to discuss the closed-door meetings. All congressional committees with an interest in Syria, from the intelligence to the armed services committees, are now being kept informed.


“I can’t comment on these reports but I have been very concerned for some time now about Syria’s stockpiles of chemical weapons and its stocks of advanced conventional weapons like shoulder-launched anti-aircraft missiles,” said House intelligence committee Chairman Mike Rogers, R-Mich. “We are not doing enough to prepare for the collapse of the Assad regime, and the dangerous vacuum it will create. Use of chemical weapons by the Assad regime would be an extremely serious escalation that would demand decisive action from the rest of the world,” he added.


Syria is believed to have one of the world’s largest chemical weapons programs, and the Assad regime has said it might use the weapons against external threats, though not against Syrians. The U.S. and Jordan share the same concern about Syria’s chemical and biological weapons — that they could fall into the wrong hands should the regime in Syria collapse and lose control of them.


___


Klapper reported from Prague. Associated Press writers Josef Federman in Jerusalem, Albert Aji in Damascus and Matthew Lee, Kimberly Dozier, and Julie Pace in Washington contributed to this report.


Europe News Headlines – Yahoo! News


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News Corp shutting down iPad newspaper ‘The Daily’ on December 15th












News Corp’s iPad newspaper “The Daily” is officially dead. Launched in February 2011, The Daily was a “ bold experiment in digital publishing and an amazing vehicle for innovation,” but like so many pioneering ideas, it “could not find a large enough audience quickly enough” to keep the publication going, according to Rupert Murdoch, the Chairman of News Corporation and Chairman and CEO of Fox Group. The Daily will officially cease publishing on December 15th and will see Jesse Angelo, its Editor-in-Chief and Executive Editor of The New York Post move into the role of Publisher for the latter. The Daily was supposed to signal a new era of app-based interactive newspapers, but alas, in a world of Flipboard, Instapaper and social media, finding a new channel to distribute and aggregate news has proven to be challenging, even for corporations with plenty of resources.


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Additional copies of ‘Lincoln’ headed to theaters












LOS ANGELES (AP) — “Lincoln” is marching to more movie theaters.


Disney, which distributed the DreamWorks film, is making additional prints of director Steven Spielberg‘s historical saga starring Daniel Day-Lewis to meet an unexpected demand that has left some moviegoers in Alaska out in the cold.












“To say that we’re encouraged by the results to date or that they’ve exceeded our expectations is an understatement,” said Dave Hollis, head of distribution at the Walt Disney Co. “We’re in the midst of making additional prints to accommodate demand and will have them available to our partners in exhibition by mid-December for what we hope will be a great run through the holiday and awards corridor.”


The film, which opened in wide release Nov. 9 and has earned $ 83.6 million in North America so far, has been unavailable at some smaller venues, such as the Gross Alaska theaters in Juneau.


But the extra prints are coming a little too late to fit the movie into the five-screen Glacier Cinemas theater during the holiday season, said Kenny Solomon-Gross, general manager of the Gross Alaska, which runs two theaters in Juneau and one in Ketchikan, Alaska.


“When we had the room for ‘Lincoln,’ Disney didn’t have a copy for us,” Solomon-Gross said Monday.


His film lineup is pretty booked through the end of the year, and he probably can’t screen “Lincoln” until after the first of the new year. Yes, the excitement over the film will have dimmed, but then the Academy Awards season will be stirring up, he said. That should kick up the buzz.


In the meantime, Solomon-Gross plans to head to Las Vegas this week and catch the film there.


___


Follow AP Entertainment Writer Derrik J. Lang on Twitter at http://www.twitter.com/derrikjlang . Associated Press writer Rachel D’Oro in Anchorage, Alaska, contributed to this report.


___


Online:


http://www.thelincolnmovie.com


Entertainment News Headlines – Yahoo! News


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Diabetes may be linked to hearing loss: study












(Reuters) – Diabetes has already been tied to an increased risk of kidney and cardiovascular troubles, nerve damage and vision loss, and now a Japanese study finds diabetics to be more than twice as likely as those without the disease to have hearing impairment.


In a review of past research on the issue, published in the Journal of Clinical Endocrinology and Metabolism, scientists found that younger diabetics were at even higher risk than older adults, though they could not explain why.












“Current meta-analysis suggests that the higher prevalence of hearing impairment in diabetic patients compared with nondiabetic patients was consistent regardless of age,” wrote lead researcher Chika Horikawa, at Niigata University Faculty of Medicine, and colleagues.


It’s not the first time researchers have found a link between diabetes and hearing loss. In 2008, researchers from the U.S. National Institutes of Health (NIH) saw similar patterns in a sample of more than 11,000 people, with people with diabetes twice as likely to have hearing loss as those without.


It’s thought that high blood sugar levels brought on by diabetes may lead to hearing loss by damaging blood vessels in the ears, said Horikawa.


Horikawa and colleagues collected information from 13 previous studies examining the link between diabetes and hearing loss and published between 1977 and 2011. Together, the data covered 7,377 diabetes and 12,817 people without the condition.


Overall, Horikawa‘s team found that diabetics were 2.15 times as likely as people without the disease to have hearing loss. But when the results were broken down by age, people under 60 had 2.61 times the risk while people over 60 hand 1.58 times higher risk.


Some experts caution that this kind of study does not prove that diabetes is directly responsible for the greater hearing loss rates.


“It doesn’t definitively answer the question, but it continues to raise an important point that patients might ask about,” said Steven Smith, a diabetes specialist at the Mayo Clinic in Rochester, Minnesota.


The researchers note that future studies that take more factors into account, such as age and noisy environment, are needed to clarify the link between diabetes and hearing loss.


Still, Horikawa told Reuters Health in an email, people should recognize that diabetics may be at risk for hearing loss based on their results.


“Furthermore, these results propose that diabetic patients are screened for hearing impairment from (an) earlier age compared with non-diabetics,” said Horikawa, adding that hearing loss has also been linked to an increased risk of depression and dementia. SOURCE: http:.//bit.ly/RIVeeW


(Reporting from New York by Andrew Seaman at Reuters Health; editing by Elaine Lies)


Diseases/Conditions News Headlines – Yahoo! News


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The Cash-Only Doctors Club












An anxious woman in her mid-40s showed up last winter at Atlas MD, a family doctor’s office in Wichita. She had lost her job as a restaurant cook, and along with it her health insurance and her home. She needed to see a doctor.


Atlas MD isn’t a free clinic. It’s a concierge medical practice, which means you can’t get an appointment unless you pay cash. Atlas MD’s two physicians, Josh Umbehr and Doug Nunamaker, don’t accept insurance. Instead, they charge most of their adult patients $ 50 a month for unlimited visits. They also offer free EKGs and biopsies and cut-rate prices on prescription drugs. Two-thirds of their patients have insurance but feel the fee is well worth it for personalized service, including house calls, the doctor’s cell-phone number, and quick responses to e-mails and Twitter messages. The rest of Umbehr and Nunamaker’s clientele are uninsured. For those patients, Atlas is the only way of seeing a family doctor regularly. Contrary to those who say concierge doctors like themselves are getting rich by focusing on personalized care at a high price, Nunamaker and Umbehr, who are in their early 30s, contend that they can grow their practice by appealing to a broader clientele.












aa082  feature doctors49  05inline  405 The Cash Only Doctors Club


“I want to be one of the 1 percent,” says Umbehr, who likes to talk business as much as he does medicine; Ayn Rand’s Atlas Shrugged inspired the name of his two-year-old practice. “But the problem with the 1 percent is there’s only 1 percent of them. If you want to build a business model that’s really far-reaching and world-changing, then it’s got to fit everybody.”


It was midway through the month when the homeless woman arrived at Atlas MD, so Nunamaker asked her for $ 25 and examined her immediately. She told him she was always tired and couldn’t keep a job. She was living in a storage shed. Nunamaker gave her a blood test, which revealed an extreme case of hypothyroidism. That explained her exhaustion. “I get why you are so fatigued,” he said. “Your thyroid isn’t working as well as it should.” He put her on medication that would boost the hormone her thyroid gland wasn’t producing and restore her vitality.


The woman stayed with Atlas MD for three months until she was feeling better. Then she left. Nunamaker gave her three months of inexpensive prescription refills and wished her well. He would have preferred to see her stay on. But he and Umbehr are proud that they were able to restore her health for $ 147, including tests and prescriptions. (They made money on her monthly retainer, but not on the tests and labs. Atlas MD provides them at cost.) They estimate that she would have paid as much as $ 1,500 if she had gone to a regular doctor. It was undeniably a good deal for her; had she required hospitalization, however, the bill would have been enormous and not covered by Atlas.


The Atlas MD doctors are eager to tell this story. They’re convinced that concierge medicine, often thought of as a luxury for the rich, is affordable for everyone and might even be the salvation of the American health-care system. “We’ve fixed health care,” Umbehr proclaims, later admitting that he tends to be “grandiose.”


The doctors at Atlas MD are among a growing number of physicians opting out of the traditional insurance-driven model. They see their older peers at traditional practices struggling to keep afloat at a time when administrative costs are rising and insurance payments have basically stayed flat. Many of these rebel doctors charge high fees and target the wealthy—visiting them at their homes, accompanying them to specialist visits, and offering them what they market as physicals fit for a CEO.


There are 4,400 concierge doctors in the U.S., 30 percent more than there were last year, according to the American Academy of Private Physicians, their professional association. “This is all doctors want to talk about,” says Jeff Goldsmith, a health-care industry analyst and trend spotter. “ ‘I want to go off the grid. I’m done billing Blue Cross. I can’t deal with this anymore. It’s destroying my life and my relationship with my patients.’ ”


Some health policymakers are encouraged by this trend. They think an increase of direct-pay doctors—especially affordable ones—could lead to better health care in the U.S., which has the highest costs and some of the worst outcomes of any wealthy nation. “I think it’s great,” says Kevin Schulman, a professor of medicine and business administration at Duke University. “We’re rediscovering that if we just ask people to pay for services, we could provide them with better value. Primary care is affordable.”


Others worry that the growth of concierge medicine will mean the affluent receive high-quality care while the rest of the country struggles to be seen by fewer and fewer doctors. “It is a step towards a two-tiered health-care system: a system where the rich get first-choice care and the not-so-rich get second-choice care,” says Kathleen Stoll, deputy executive director of Families USA, a health-care consumer advocacy group.


This much is certain: There will be greater demand for primary-care physicians because of President Obama’s Affordable Care Act. “Love it or hate it,” Atlas MD’s Umbehr says of Obamacare, “it’s going to make it harder for you to see your doctor.”
 
 
Primary-care physicians have long complained of being the poor men of their industry. Their median salary is $ 160,000 a year—roughly half of an anesthesiologist’s—but rising overhead, more paperwork, and packed waiting rooms are propelling ever-greater numbers to shed patients and charge a retainer. In 2011 the average American medical practice spent $ 82,975 per doctor dealing with insurers, according to the Commonwealth Fund. That same doctor has 3,281 active patients over a three-year period, says the American Academy of Family Physicians. She rarely has time to see them for more than a few minutes. The attraction of concierge medicine for her isn’t hard to fathom: She can winnow down her patient roster, spend more time with each, and do away with her insurance-related headaches.


aa082  feature doctors49  03  inline405 The Cash Only Doctors ClubPhotograph by Ryan Lowry for Bloomberg BusinessweekPriority Physicians charges about $ 5,500 per patient per year for personalized service including house calls, prescription delivery, and unlimited face time


It will only become more enticing in 2014 when the Affordable Care Act’s individual mandate requires everyone to be insured. The law will enable 30 million previously uninsured people to get coverage through an expansion of Medicaid. They’ll need primary care, but it’s not yet clear who will give it to them. By 2020, the Association of American Medical Colleges estimates, there will be 45,000 fewer primary-care doctors than the U.S. needs. “For the last 13 years, very few students have been going into it,” says Patrick Dowling, chairman of the department of family medicine at the University of California-Los Angeles’s David Geffen School of Medicine. “What motivates medical school students is income, just like everyone else.”


Proponents of concierge medicine insist that more time with each patient allows them to provide holistic care that can prevent diseases such as diabetes that are major drivers of health-care costs in America and keep people out of hospital emergency rooms. Garrison Bliss, co-founder of Qliance, a low-cost concierge medicine company based in Seattle, estimates that if everybody in the nation went to one of his doctors, the country would save $ 268 billion annually. In 2010, Qliance says, its clients visited emergency rooms 65 percent less than similar patients. Thirty-five percent fewer of them needed to be hospitalized. They required 66 percent fewer specialist visits.


But when doctors go the concierge route, they often reduce their patient roster as much as 80 percent, creating more scarcity. “There aren’t enough primary-care people around now,” says Arthur Caplan, director of medical ethics at the NYU Langone Medical Center. “When concierge practices spread, that means more and more people will be left without any access to primary care.”


It also affects other doctors. Russell Phillips is the director of the Harvard Medical School Center for Primary Care and a practicing physician at Beth Israel Deaconess Medical Center. “We have a handful of doctors affiliated with Beth Israel who have done this,” he says. “Every time it happens, it is an event. We have to figure who is going to take their patients.”


As consumer advocates and policymakers fret, concierge doctors are making money. Corporate interests are getting involved, too. In 2009, Procter & Gamble (PG) bought MDVIP, a national concierge medical franchise, for an undisclosed amount. Venture capitalists are investing in direct-pay practices, and private equity firms are interested. “When the private equity folks come to our conferences, they say the winds are in the sails of both supply and demand for private medicine,” says Tom Blue, executive director of the American Academy of Private Physicians. “That spells opportunity.”
 
 
It’s a Thursday morning in September, and Howard Maron, considered the father of concierge medicine by many, is sitting at a table in the Gallery restaurant at the Carlyle hotel on the Upper East Side of Manhattan. With his bushy white hair and a white mustache, the 61-year-old doctor looks like Ted Turner. He has a similar bravado. He went to UCLA Medical School. In 1980 he started a traditional primary-care practice in Seattle with three doctors. Maron had 3,000 patients. He says that as long as 30 of them were sick on a given day, his office was full, and he made money.


In 1982, Maron became the team physician for the Seattle SuperSonics. It wasn’t a full-time job. But when the team had away games, he tagged along and looked after the basketball players. Maron arranged for sick SuperSonics to see the best specialists wherever they were on their road trips. He would get players into hospitals under assumed names to keep them out of the papers. “It was spare-no-expense,” he says wistfully. “It was ‘Get it done and get it done right.’ ”


In 1996, Maron founded MD2 International, hoping to offer the same level of care to a select group of patients. He thought he could do this if he and his partner, Scott Hall, saw only 50 families. MD2 would charge them $ 25,000 a year. Maron says other Seattle physicians thought he was crazy: “They said, ‘Nobody is going to pay you.’ ”


Maron says he quickly attracted enough patients. “When you open up an office and you know that you’re going to be limited to only 50 families, the shoe is on the other foot,” he boasts. “They think they’re interviewing you, but you’re interviewing them. You want very special people because this is it. This is your cadre.”He decorated his office with marble bathrooms and antique sculpture. He gave clients lengthy physicals. He got them appointments to see the best specialists in Seattle. And his patients never had to fill out a form, because MD2 didn’t accept insurance. Maron compares the experience to traveling by private jet. “I fly private, too,” he adds.


Maron opened offices in San Francisco, Dallas, Chicago, and Portland, Ore. Much to his consternation, other concierge doctors emerged and charged less. “They dumbed the model down,” Maron grouses. “Really, the only person who has their finger on the pulse of this is me.”


aa082  feature doctors49  02  inline202 The Cash Only Doctors ClubRyan Lowry for Bloomberg BusinessweekCraig Veatch


In 2002, Craig Veatch and Matthew Priddy of Priority Physicians started tending to patients in Indianapolis with substantial incomes. Each saw no more than 200 patients and charged most adults $ 5,500 a year. “We knew there were people out in Seattle charging $ 10,000 to $ 25,000 a year,” says Veatch. “We just felt that the cost of living is a little bit lower in the Midwest.”


The doctors at Priority Physicians also refuse insurance, but they do make house calls. They drive their patients to the hospital when they need surgery. (Patients use their insurance to pay for visits to specialists and hospitals.) They even make pharmacy runs for them.


They also insist their services are not exclusively for the well-heeled. “We have patients who say, “I’ll forgo an extra vacation so I can come and see you,” says Shelagh Fraser, a doctor who joined Priority in 2006. “I mean, we certainly have some very wealthy patients,” Priddy adds. “But we have many patients whom you would consider middle class who employ our services instead of lease a BMW for $ 800 a month. They just drive a cheaper car.”


Last year, Tim Herd, chief executive of a local property and casualty insurance company, came to Priority Physicians for a flu shot. He brought his two children, who are in college. They marveled at the plush carpets, heavy wooden doors, and black leather sofas in the exam rooms. “My kids said, ‘Dad, no wonder you like this place. It’s like the Four Seasons of doctors’ offices,’ ” Herd chuckles.


Practices offering cheaper models sprang up elsewhere. The largest is MDVIP, headquartered in Boca Raton, Fla., and founded in 2000. Each MDVIP doctor can have 600 patients. “Six hundred is really the maximum that you could have to provide that annual exam and follow up,” says MDVIP President Mark Murrison. MDVIP charges an average annual fee of $ 1,650. It also bills insurance companies for procedures. It has 580 doctors in 40 states and 200,000 patients. MDVIP also has an aggressive growth strategy: It says it recruits older doctors willing to shed many patients and tend to those who pay extra. Some people find this approach ethically dubious. “There has been a long-standing prohibition within the medical profession against abandonment,” says NYU’s Caplan. “Once you have a long-term relationship with a patient, you are supposed to stick with them or find them someone else.”


MDVIP says its physicians try hard to place former patients. Still, some of them feel burned. In a letter published in the Memphis Commercial Appeal after a local practitioner joined MDVIP, one ex-patient asked, “What happened to the Hippocratic Oath?”
 
 
Some doctors had a more egalitarian vision for concierge medicine. One of them was Bliss, who practiced with Maron before Maron departed to create MD2. “Howard went off and started his practice for $ 25,000 a year per patient,” Bliss says. “You know, by invitation only? I didn’t have any interest in that. Why would I want to take care of 50 rich families?”


aa082  feature doctorschart49 405b The Cash Only Doctors Club


A self-described liberal in medical school who didn’t care about business, Bliss sat down with his spreadsheets and came up with a different model for Seattle Medical Associates, which he founded in 1981 and reopened in 1997. The new practice didn’t take insurance. Instead, the highest price he and his partner, Mitchell Karton, charged was $ 65 a month. Each doctor could see 800 patients.


In 2007, Bliss was restless. One of his patients, a venture capitalist, urged him to create a company that could expand nationally. So he started Qliance, a concierge medicine provider with five offices in Washington State. Qliance, which has since raised $ 17 million in venture capital, still charges most patients $ 65 a month. Its 5,000 clients include truck drivers, grocery store clerks, and other blue-collar workers. They can contact their doctor at any hour. When they visit an office, they are guaranteed at least half an hour with their doctor. Like wealthy patients at a pricier concierge practice, Qliance’s patrons often have insurance, but are willing to pay extra for convenience.


“One time my old doctor was giving me a physical,” says Jed Aldridge, a retired 65-year-old firefighter and Qliance patient who lives in a Seattle suburb. “After 10 minutes he looked at his watch and said, ‘Our 15 minutes are almost up.’ Are you kidding? I’m getting older. I have more than 15 minutes of medical issues to talk about.” Aldridge says he never feels rushed now.


Meanwhile, in Wichita, Atlas MD began collecting $ 50 a month for most patients in 2010. Umbehr and Nunamaker say they can charge a fraction of what other concierge doctors ask because they run a lean operation. They need no office manager to handle insurance, and the only other employee is Jeannie O’Callaghan, a registered nurse. The doctors often answer the phone themselves. They make coffee and wipe off the counters.


Both occasionally work in the emergency room at a local hospital to cover their startup costs. Still, each expects to make $ 200,000 this year. “The math does work out,” Umbehr says. “Some of the people we went to medical school with are coming out and signing $ 140,000-a-year contracts with hospitals.”


On a Monday morning in October, Umbehr and Nunamaker are sitting in their expansive, high-ceilinged waiting room. It’s almost 9 a.m., a time when most physicians’ offices are bustling with patients. Atlas MD is strangely peaceful. The first patient visit isn’t scheduled for another half-hour.


Nunamaker and Umbehr spend much of their time interacting with their patients online, and on this day, Nunamaker is trading e-mails with a woman whose son has strep throat. He holds up a fairly gruesome image on his iPhone of the child’s throat. “Enlarged tonsils, pus pockets, sore throat, a fever,” he says. There’s no reason for the mother to bring her sick child into the office to hear that he needs a stronger antibiotic. He can handle that digitally. Umbehr shares an even more unsettling phone image, a boy with an eye infection. He has been corresponding with the boy’s mother and decides the infection isn’t serious. He says the mother manages a call center and can’t afford to leave work. He e-mails a prescription to a Walgreens (WAG) near her job. That way, she can pick up the medication on her lunch hour. “She’s making $ 24,000 a year and has a concierge doctor,” Umbehr boasts.


The question is whether such inexpensive concierge care can be a model for everybody. Ezekiel Emanuel, a former White House health-care policy adviser and one of the architects of the Affordable Care Act, doesn’t think so. “The problem is, it excludes specialty care, complex diagnostics, hospitalization,” he says. “People need insurance. They need the whole product.”


Conceding the point, some of the more forward thinkers in the concierge movement are trying to figure out how to build a new model for primary care by combining their services along with insurance. In 2012 the average premium for an employer-provided insurance policy for a family of four climbed to a record high of $ 20,728, according to Milliman, a health-care consultancy. What if families could purchase cheap concierge care from a provider like Atlas MD and supplement it with lower-priced insurance? Wouldn’t there be a cost savings? “Health insurance should work more like car insurance,” says Umbehr. “We have car insurance for all the big stuff, but we pay for gas, tires, and oil changes ourselves.”


Qliance just launched a pilot program with Cigna (CI) that does something like that. Meanwhile, Bliss has pitched a plan to help Medicare save money. “We’d love to do that,” he says. “We think we could do it for $ 100 per patient and save them 20 to 30 percent of their health-care costs. But Medicare won’t recognize us.”


Traditional high-priced concierge doctors would be well advised to pay attention. If they turn away too many patients in the middle of a doctor shortage, they may risk a political backlash and increased regulation. Nobody in the profession is more worried about this than its founder, Howard Maron. “Guess who is going to be the victim of the blame game?” he warns. “Doctors who have opted out, doctors who refuse to see patients. Who is that? Us.”


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Egypt’s anti-Morsi rebellion of judges is complete












CAIRO (AP) — Egypt‘s rebellion of the judges against President Mohammed Morsi became complete on Sunday with the country’s highest court declaring an open-ended strike on the day it was supposed to rule on the legitimacy of two key assemblies controlled by allies of the Islamist leader.


The strike by the Supreme Constitutional Court and opposition plans to march on the presidential palace on Tuesday take the country’s latest political crisis to a level not seen in the nearly two years of turmoil since Hosni Mubarak‘s ouster in a popular uprising.












Judges from the country’s highest appeals court and its sister lower court were already on an indefinite strike, joining colleagues from other tribunals who suspended work last week to protest what they saw as Morsi‘s assault on the judiciary.


The last time Egypt had an all-out strike by the judiciary was in 1919, when judges joined an uprising against British colonial rule.


The standoff began when Morsi issued decrees on Nov. 22 giving him near-absolute powers that granted himself and the Islamist-dominated assembly drafting the new constitution immunity from the courts.


The constitutional panel then raced in a marathon session last week to vote on the charter’s 236 clauses without the participation of liberal and Christian members. The fast-track hearing pre-empted a decision from the Supreme Constitutional Court that was widely expected to dissolve the constituent assembly.


The judges on Sunday postponed their ruling on that case just before they went on strike.


Without a functioning justice system, Egypt will be plunged even deeper into turmoil. It has already seen a dramatic surge in crime after the uprising, while state authority is being challenged in many aspects of life and the courts are burdened by a massive backlog of cases.


“The country cannot function for long like this, something has to give,” said Negad Borai, a private law firm director and a rights activist. ‘We are in a country without courts of law and a president with all the powers in his hands. This is a clear-cut dictatorial climate,” he said.


Mohamed Abdel-Aziz, a rights lawyer, said the strike by the judges will impact everything from divorce and theft to financial disputes that, in some cases, could involve foreign investors.


“Ordinary citizens affected by the strike will become curious about the details of the current political crisis and could possibly make a choice to join the protests,” he said.


The Judges Club, a union with 9,500 members, said late Sunday that judges would not, as customary, oversee the national referendum Morsi called for Dec. 15 on the draft constitution hammered out and hurriedly voted on last week.


The absence of their oversight would raise more questions about the validity of the vote. If the draft is passed in the referendum, parliamentary elections are to follow two months later and they too may not have judicial supervision.


The judges say they will remain on strike until Morsi rescinds his decrees, which the Egyptian leader said were temporary and needed to protect the nation’s path to democratic rule.


For now, however, Morsi has to contend with the fury of the judiciary.


The constitutional court called Sunday “the Egyptian judiciary’s blackest day on record.”


It described the scene outside the Nile-side court complex, where thousands of Islamist demonstrators gathered since the early morning hours carrying banners denouncing the tribunal and some of its judges.


A statement by the court, which swore Morsi into office on June 30, said its judges approached the complex but turned back when they saw the protesters blocking entrances and climbing over its fences. They feared for their safety, it added.


“The judges of the Supreme Constitutional Court were left with no choice but to announce to the glorious people of Egypt that they cannot carry out their sacred mission in this charged atmosphere,” said the statement, which was carried by state news agency MENA.


Supporters of Morsi, who hails from the Islamic fundamentalist Muslim Brotherhood, claim that the court’s judges remain loyal to Mubarak, who appointed them, and accuse them of trying to derail Egypt’s transition to democratic rule.


In addition to the high court’s expected ruling Sunday on the legitimacy of the constitution-drafting panel, it was also expected to rule on another body dominated by Morsi supporters, parliament’s upper chamber.


Though Morsi’s Nov. 22 decrees provide immunity to both bodies against the courts, a ruling that declares the two illegitimate would have vast symbolic significance, casting doubt on the standing of both.


The Brotherhood’s political arm, the Freedom and Justice party, sought to justify the action of its supporters outside the court as a peaceful protest. It reiterated its charge that some members of the judiciary were part and parcel of Mubarak’s autocratic policies.


“The wrong practices by a minority of judges and their preoccupation with politics … will not take away the respect people have for the judiciary,” it said.


Its explanation, however, failed to calm the anger felt by many activists and politicians.


President Morsi must take responsibility before the entire world for terrorizing the judiciary,” veteran rights campaigner and opposition leader Abdel-Halim Kandil wrote in his Twitter account about the events outside the constitutional court.


Liberal activist and former lawmaker Amr Hamzawy warned what is ahead may be worse.


“The president and his group (the Muslim Brotherhood) are leading Egypt into a period of darkness par excellence,” he said. “He made a dictatorial decision to hold a referendum on an illegal constitution that divides society, then a siege of the judiciary to terrorize it.”


Egypt has been rocked by several bouts of unrest, some violent, since Mubarak was forced to step down in the face of a popular uprising. But the current one is probably the worst.


Morsi’s decrees gave him powers that none of his four predecessors since the ouster of the monarchy 60 years ago ever had. Opposition leaders countered that he turned himself into a new “pharaoh” and a dictator even worse than his immediate predecessor Mubarak.


Then, following his order, the constituent assembly rushed a vote on the draft constitution in an all-night session.


The draft has a new article that seeks to define what the “principles” of Islamic law are by pointing to theological doctrines and their rules. Another new article states that Egypt’s most respected Islamic institution, Al-Azhar, must be consulted on any matters related to Shariah law, a measure critics fear could lead to oversight of legislation by clerics.


Rights groups have pointed out that virtually the only references to women relate to the home and family, that the new charter uses overly broad language with respect to the state protecting “ethics and morals” and fails to outlaw gender discrimination.


At times the process appeared slap-dash, with fixes to missing phrasing and even several entirely new articles proposed, written and voted on in the hours just before sunrise.


The decrees and the vote on the constitution draft galvanized the fractured, mostly secular opposition, with senior leaders setting aside differences and egos to form a united front in the face of Morsi, whose offer on Saturday for a national dialogue is yet to find takers.


The opposition brought out at least 200,000 protesters to Cairo’s Tahrir Square on Tuesday and a comparable number Friday to press demands that the decrees be rescinded. The Islamists responded Saturday with massive rallies in Cairo and across much of Egypt.


The opposition is raising the stakes with plans to march on Morsi’ palace on Tuesday, a move last seen on Feb. 11, 2011 when tens of thousands of protesters marched from Tahrir Square to Mubarak’s palace in the Heliopolis district to force him out. Mubarak stepped down that day, but Morsi is highly unlikely to follow suit on Tuesday.


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Euro zone crisis drags down European ad spending: report












LONDON (Reuters) – The euro zone crisis has left Western Europe the only world region to see a fall in advertising spending this year, market research group ZenithOptimedia said.


The forecasting group said advertising expenditure in Western Europe fell 2.2 percent to $ 106.8 billion this year compared with an average increase of 3.3 percent worldwide.












North American ad spending rose 4.1 percent to $ 171.9 billion and Asia’s expenditure was up 6.1 percent to $ 140.1 billion this year.


“Developing markets, social media and online video are all growing rapidly, supporting continued expansion in global ad expenditure despite stagnation in the eurozone,” said Steve King, global chief executive of ZenithOptimedia Group.


The company, part of advertising agency Publicis, also said European ad spending would be flat next year before growing by about 2 percent in 2014 and 2015.


This leaves Europe lagging faster-growing regions such North America, which will grow by 3.5 percent next year, as well as Asia (5.5 percent) and Latin America (10 percent).


“The euro zone crisis is dragging down economic growth at the moment,” ZenithOptimedia said on Monday.


“Because the eurozone is in recession, its imports from other countries are slowing down or shrinking, and the risk of eurozone collapse adds to global uncertainty, leading companies to hoard cash instead of investing in growth,” the firm said in an emailed statement.


Ad spending generally tracks economic growth, so recessions tend to hit the shares of advertising agencies, including market leaders WPP, Omnicom, Interpublic Group and Publicis.


ZenithOptimedia said global ad expenditure would rise 4.1 percent next year to reach $ 518 billion, driven largely by faster growth in the developing markets.


(Editing by Helen Massy-Beresford)


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Young down by boardwalk for benefit show












NEW YORK (AP) — Neil Young said Sunday that he couldn’t see performing in the area devastated by Superstorm Sandy without doing something to help people who were affected by it.


Young and his longtime backing band, Crazy Horse, will hold a benefit concert for the American Red Cross‘ storm relief effort Thursday at the Borgata Hotel Casino & Spa in Atlantic City. The New Jersey coastline areas were hit hard by the storm in late October.












People in the New York area who suffered damage in the storm have been supporting him for 40 years, he said.


“I couldn’t see coming back here and just playing and have it be business as usual,” he said. Young is touring in the area, with concerts scheduled for Monday in Brooklyn and Tuesday in Bridgeport, Conn.


Minimum ticket prices for the standing-room show in Atlantic City will be $ 75 and $ 150, although Young notes there’s no maximum. He hopes to raise several hundred thousand dollars for the Red Cross.


Young said he was invited to join the Dec. 12 benefit at New York’s Madison Square Garden that will feature Bruce Springsteen, Paul McCartney, the Who, Kanye West and others, but had other obligations. Besides, there’s enough star power there, he said.


“It wasn’t going to make much difference whether I was there or not, so I decided to go someplace where I could make a difference,” he said.


Young performed at a televised benefit in 2001 following the Sept. 11 terrorist attacks, memorably covering John Lennon’s “Imagine.”


Fans can expect a two-hour plus rock show on Thursday with opening band Everest. No special guests are planned, although Young issued an invitation to “anyone who wants to come in and play with us that we know and we know can play.”


It’s hard to resist wondering whether Young’s epic “Like a Hurricane” will make it onto the set list, given the occasion.


“Anything’s possible,” Young said. “We have the equipment.”


Entertainment News Headlines – Yahoo! News


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